Publications & Conferences

My work, integrating technological development with cross-scale biological applications, thus far led to 27 peer-reviewed publications (8 (co-)first- or last-authored) with 1000+ citations (h-index = 15), 14 first-author conference contributions (including invited talks), and 1 patent.

A complete list of my publications is available on Google Scholar and ORCID, while selected publications are listed below.

PEER-REVIEWED PUBLICATIONS

  1. B. Haider, S. Middya, D. J. Lloyd-Davies-Sánchez, N. F. Läubli, et al. NeuroSuite for long-term functional and structural studies of air-liquid interface cerebral organoids. Advanced Science (2026), e19893. 10.1002/advs.202519893
  2. F. Hirsch, N. F. Läubli, A. Kelkar, et al. Impairment of neuronal activity occurs at the early stages of the aggregation cascade of Aβ1–42 and mutant Tau. Disease Models & Mechanisms (2026) 19, dmm052295. 10.1242/dmm.052295
  3. S. Collins, L. van Vliet, F. Gielen, et al., N. F. Läubli, et al. A microfluidic fluorescence lifetime screening platform bridges in vitro and in vivo formats and enables discovery of amyloid-β aggregation inhibitors. Nature Communications, accepted.
  4. S. J. Resnick, S. Qamar, P. Krishna, et al., N. F. Läubli, et al. Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity. Nature Communications (2025) 16, 10285. 10.1038/s41467-025-65178-0
  5. S. Kapsiani, N. F. Läubli, E. N. Ward, et al. Deep learning for fluorescence lifetime predictions enables high-throughput in vivo imaging. Journal of the American Chemical Society (2025) 147, 22609–22621. 10.1021/jacs.5c03749
  6. S. Kapsiani, N. F. Läubli, E. N. Ward, M. Shehata, C. F. Kaminski and G. S. Kaminski Schierle. FLIMPA: A versatile software for fluorescence lifetime imaging microscopy phasor analysis. Analytical Chemistry (2025) 97, 11382–11387. 10.1021/acs.analchem.5c00495
  7. M. Brockhoff, J. Träuble, S. Middya, et al., N. F. Läubli, et al. PseudoSorter: A self-supervised spike sorting approach applied to reveal Tau-induced reductions in neuronal activity. Science Advances (2025) 11, eadr4155. 10.1126/sciadv.adr4155
  8. M. Lu, E. Hui, M. Brockhoff, et al., N. F. Läubli, S. Hofmann, C. F. Kaminski and G. S. Kaminski Schierle. Graphene microelectrode arrays, 4D structured illumination microscopy and machine-learning spike sorting permit analysis of ultrastructural neuronal changes during neuronal signalling. Advanced Science (2024) 11, 2402967. 10.1002/advs.202402967
  9. B. Mazumder, M. Lu, H. Rahmoune, et al., N. F. Läubli, C. F. Kaminski and G. S. Kaminski Schierle. Sea cucumber-derived extract can protect skin cells from oxidative DNA damage and mitochondrial degradation, and promote wound healing. Biomedicine & Pharmacotherapy (2024) 180, 117466. 10.1016/j.biopha.2024.117466
  10. A. E. Paiva, M. S. Gerlt, N. F. Läubli, et al. High-aspect-ratio nanoscale pores through BCP-based metal oxide masks and advanced dry etching. ACS Applied Materials & Interfaces (2023) 15, 57960–57969. 10.1021/acsami.3c09863
  11. M. Lu, C. N. Christensen, J. M. Weber, et al., N. F. Läubli, et al. ERnet: A tool for the semantic segmentation and quantitative analysis of endoplasmic-reticulum topology for video-rate super-resolution imaging. Nature Methods (2023) 20, 569–579. 10.1038/s41592-023-01815-0
  12. T. Clerc, S. Boscq, R. Attia, G. S. Kaminski Schierle, B. Charrier* and N. F. Läubli*. Cultivation and imaging of S. latissima embryo monolayered cell sheets inside microfluidic devices. Bioengineering (2022) 9, 718. 10.3390/bioengineering9110718
  13. E. Saikia, N. F. Läubli, H. Vogler, et al. Mechanical factors contributing to the Venus flytrap’s rate-dependent response to stimuli. Biomechanics and Modeling in Mechanobiology (2021) 20, 2287–2297. 10.1007/s10237-021-01507-8
  14. B. Charrier*, S. Boscq, B. J. Nelson and N. F. Läubli*. Growth and labelling of cell-wall components of the brown alga Ectocarpus in microfluidic chips. Frontiers in Marine Science (2021) 8, 745654. 10.3389/fmars.2021.745654
  15. N. F. Läubli*, M. S. Gerlt*, A. Wüthrich, et al. Embedded microbubbles for acoustic manipulation of single cells and microfluidic applications. Analytical Chemistry (2021) 93, 9760–9770. 10.1021/acs.analchem.1c01209
  16. N. F. Läubli*, J. T. Burri*, J. Marquard, et al. 3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy. Nature Communications (2021) 12, 2583. 10.1038/s41467-021-22718-8
  17. M. S. Gerlt*, N. F. Läubli*, M. Manser, B. J. Nelson and J. Dual. Reduced etch lag and high aspect ratios by deep reactive ion etching. Micromachines (2021) 12, 542. 10.3390/mi12050542
  18. E. Saikia, N. F. Läubli, J. T. Burri, et al. Kinematics governing mechanotransduction in the sensory hair of the Venus flytrap. International Journal of Molecular Sciences (2021) 22, 280. 10.3390/ijms22010280
  19. J. T. Burri*, E. Saikia*, N. F. Läubli*, et al. A single touch can provide sufficient mechanical stimulation to trigger Venus flytrap closure. PLOS Biology (2020) 18, e3000740. 10.1371/journal.pbio.3000740
  20. N. F. Läubli, N. Shamsudhin, H. Vogler, et al. 3D manipulation and imaging of plant cells using acoustically activated microbubbles. Small Methods (2019) 3, 1800527. 10.1002/smtd.201800527
  21. F. Mushtaq, H. Torlakcik, M. Hoop, et al., N. Läubli, et al. Motile piezoelectric nanoeels for targeted drug delivery. Advanced Functional Materials (2019) 29, 1808135. 10.1002/adfm.201808135
  22. J. T. Burri, H. Vogler, G. Munglani, N. F. Läubli, U. Grossniklaus and B. J. Nelson. A microrobotic system for simultaneous measurement of turgor pressure and cell-wall elasticity of individual growing plant cells. IEEE Robotics and Automation Letters (2019) 4, 641–646. 10.1109/LRA.2019.2892582
  23. J. T. Burri, H. Vogler, N. F. Läubli, C. Hu, U. Grossniklaus and B. J. Nelson. Feeling the force: How pollen tubes deal with obstacles. New Phytologist (2018) 220, 187–195. 10.1111/nph.15260
  24. D. Ahmed, T. Baasch, N. Blondel, N. Läubli, J. Dual and B. J. Nelson. Neutrophil-inspired propulsion in a combined acoustic and magnetic field. Nature Communications (2017) 8, 770. 10.1038/s41467-017-00845-5
  25. C. Hu, H. Vogler, M. Aellen, et al., N. Läubli, U. Grossniklaus, S. Pané and B. J. Nelson. High-precision localized proton gradients and fluxes generated by a microelectrode device induce differential growth behaviours of pollen tubes. Lab on a Chip (2017) 17, 671–680. 10.1039/C6LC01307D
  26. N. Läubli, N. Shamsudhin, D. Ahmed and B. J. Nelson. Controlled three-dimensional rotation of single cells using acoustic waves. Procedia CIRP (2017) 65, 93–98. 10.1016/j.procir.2017.04.028
  27. N. Shamsudhin, N. Läubli, H. B. Atakan, et al. Massively parallelized pollen-tube guidance and mechanical measurements on a lab-on-a-chip platform. PLOS ONE (2016) 11, e0168138. 10.1371/journal.pone.0168138

MANUSCRIPTS IN REVIEW OR PREPARATION

N. F. Läubli, C. Cutts, J. Hepworth, A. Fernandez-Villegas and G. S. Kaminski Schierle. CelBA: An open-source toolset for C. elegans behavioural analysis. In preparation.

N. F. Läubli, C. K. Yuen, L. Fricker, F. Dewulf, A. Fernandez-Villegas and G. S. Kaminski Schierle. Increased dietary cholesterol modulates neuronal activity during oligomeric phases of tauopathy. In preparation.

S. Kapsiani, S. Vora, A. Fernandez-Villegas, C. F. Kaminski, N. F. Läubli* and G. S. Kaminski Schierle*. Discovery of TDP-43 aggregation inhibitors via a hybrid machine-learning framework. Under review.

Y. Feng, A. D. Stephens, P. Vallejo Ramirez, et al., N. F. Läubli, et al. Endogenous α-synuclein facilitates spontaneous dopamine release in a calcium- and phosphorylation-dependent manner. Under review.

M. Narciso, R. Jackob, A. Stracuzzi, et al., N. F. Läubli, et al. Senescence shifts endothelial alignment response to shear stress via E-selectin-dependent mechanisms. Under review.

TALKS & CONFERENCE CONTRIBUTIONS

2026
Cholesterol Modulates Neuronal Activity in Human Tau-Overexpressing C. elegans, Centre for Physical Biology Annual Day, Cambridge, UK.
2026
Cholesterol Modulates Neuronal Activity in Human Tau-Overexpressing C. elegans, Brain Conference, London, UK.
2026
Cholesterol Modulates Neuronal Activity in Human Tau-Overexpressing C. elegans, Alzheimer’s Research UK Research Conference, Manchester, UK.
2024
Studying Neuronal Function and Dysfunction in Neurodegenerative Disease Across Scales, CIND Neurotechnology and Neurocomputation, Cambridge, UK. Invited.
2023
Passive Microfluidics for the Characterisation of Neuronal Signals in Live Nematodes, Physics of Life Conference, Harrogate, UK.
2022
Acoustofluidic Embedded Microbubbles as an Alternative to Common Microstructures, Workshop on Capillary Micromanipulation, online.
2022
Localised Mechanical Characterisation of Small Organisms Enabled through Microbubble-Based Manipulation, Acoustofluidics Conference, Glasgow, UK.
2022
Characterisation of Cells and Small Organisms Using Acoustic Manipulation, MARSS, Toronto, Canada. Invited.
2022
Investigation of Model Organisms: From Single Cells to Dragons, MSRL Symposium, ETH Zurich, Switzerland. Invited.
2021
Microfluidic Manipulation through Acoustically Controlled Embedded Microbubbles, Workshop on Capillary Micromanipulation, online.
2019
Manipulation and Characterisation at Small Scales: From Single Cells to Organisms, FEMTO-ST Workshop, Besançon, France. Invited.
2019
Micromechanical Characterisation of Plants: From Single Cells to Plant Tissue, MARSS, Helsinki, Finland.
2017
Acoustic Manipulation of Single Pollen Grains, International SystemsX.ch Conference, Zurich, Switzerland.
2017
Controlled Three-Dimensional Rotation of Single Cells Using Acoustic Waves, CIRP Conference on BioManufacturing, Chicago, USA.